MegaPre™

PRECISION PREBIOTIC™

MegaPre™ is the first Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria. MegaPre™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.

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At a Glance

Cutting-edge Precision Prebiotic™

MegaPre™ is a cutting-edge Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial, keystone bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria.

Prebiotics are non-digestible fibers that feed the bacteria living in your gut. However, most prebiotics on the market can feed both harmful and beneficial gut bacteria, which can exacerbate digestive issues. Keystone bacteria like bacterium prausnitzii, and Bifidobacteria are very important for human health, but their populations can be easily diminished by antibiotics, stress, diet, glyphosate, and other environmental toxins.

Microbial Diversity

Keystone bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria are very important for human health, but their populations can be easily diminished by antibiotics, stress, diet, glyphosate, and other environmental toxins.

Functional Fibers

MegaPre™ contains a proprietary blend of functional fibers that specifically feed these keystone bacteria. This unique blend is made up of clinically-tested-and-published, non-digestible oligosaccharides, derived from non-GMO green and gold kiwi fruit, non-GMO corn cob, and rBST-free cow’s milk

Source Prebiotic Fiber
Non-GMO green and gold kiwifruit Fructooligosaccharides
Non-GMO corn cob Xylooligosaccharides
rBST-free cow’s milk Galactooligosaccharides

The findings of these oligosaccharide studies are quite impressive:

  • FOS increased populations of A. mucin by 8,000% in 5 weeks
  • FOS increased populations of F. prau by 100% in 4 weeks
  • GOS increased populations of Bifido by 10% in 6 weeks
  • XOS increased populations of Bifido by 9% in 8 weeks

Increasing populations of these protective bacteria is an integral part of reinforcing a healthy gut microbiome.

Nourish the powerful ecosystem in your gut with MegaPre™ today!

MegaPre Capsule Dosing Instructions

Ages 2+: Start with 3 capsules daily for one week, then increase to 6 scoop daily with or without food, or as directed by your healthcare practitioner. Eventually, the capsules can be opened and mixed with water or liquid of your choice.

Week 1

3 capsules daily

Week 2+

6 capsules daily

Research

Blatchford P, Stoklosinski H, Eady S, et al.

Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. J Nutr Sci. 2017; 6: e52.

Everard A, Lazarevic V, Derrien M, et al.

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice. Diabetes. 2011 Nov; 60(11): 2775–2786.

Yang J, Summanen PH, Henning SM, et al.

Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study. Front Physiol. 2015; 6: 216.

Collado MC, Derrien M, Isolauri E, de Vos WM, Salminen S.

Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol. 2007;73: 7767–7770.

Depeint F, Tzortzis G, Vulevic J, et al.

Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of Bifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. Am J Clin Nutr. 2008;87:785-91.

Vulevic J, Juric A, Tzortzis G, and Gibson GR.

A Mixture of trans-Galactooligosaccharides Reduces Markers of Metabolic Syndrome and Modulates the Fecal Microbiota and Immune Function of Overweight Adults. J Nutr. 2013;143(3):324-31.

Chelakkot C, Choi Y, Kim DK, et al.

Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions. Experimental & Molecular Medicine. 2018;50:e450.