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EpicDefense

Immune Support

EpicDefense is a science-backed, next-generation immunobiotic formula that supports year-round immune defense, providing daily and seasonal wellness. It regulates immunity, optimizes mucosal immune function, boosts immune signaling molecules, and supports respiratory and nasal comfort.**

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At a Glance

EpicDefense Benefits

Key Features

Key Features

What are Immunobiotics?

Probiotics are great for your gut, helping digestion and keeping your body balanced. Now discover the next evolution in human microbiome science —immunobiotics— the new standard in immune wellness.

Immunobiotics are defined as “microbes that promote immune health by activating gut microbiome-induced immunity.” These powerful probiotics and postbiotics supercharge your immune system, working through your gut microbiome to fortify your body’s natural defenses—creating the ripple effect of whole-body health.

EpicDefense brings you potent, clinically studied next-generation immunobiotics—LGG®, BB-12®, and EpiCor®—backed by science to ease seasonal challenges, promote nasal and respiratory comfort, and support daily, year-round immunity. Our formula also includes Albion® Minerals’ immune-promoting zinc bisglycinate, chelated for ultra absorption and bioavailability.

Embrace a stronger, healthier you with EpicDefense—the new era of immunobiotic-powered immune wellness!

Q. How do I take EpicDefense?

Take 1 capsule per day or as directed by your healthcare practitioner.

Q. What are immunobiotics?

Immunobiotics are special types of probiotics, postbiotics, or microbial components, like LGG®, BB-12®, and EpiCor®, that help support your immune system. They work in your gut microbiome to promote a healthy balance of good bacteria, strengthen your body’s natural defenses, and support nasal and respiratory comfort during daily and seasonal challenges.

Q. How are immunobiotics different from regular probiotics?

Regular probiotics mainly help with digestion and gut microbiome health. Immunobiotics do that too, but they also directly support your immune system by encouraging beneficial bacteria growth, boosting immune cell activities, promoting antibody production, and strengthening the gut’s protective lining.

Q. Does EpicDefense contain allergens?

These capsules are free from 9 major allergens and contain no artificial colorings or flavorings.

Q. Is EpicDefense safe to take during pregnancy?

Yes, EpicDefense is generally considered safe to use during pregnancy and breastfeeding. However, please consult your healthcare provider before starting any new supplement to ensure it's appropriate for your situation.

Q. What are the formulation standards for EpicDefense?

Tested for potency, purity, and safety
Solvent-free during production
Soy-free • Dairy-free • Non-GMO

EpicDefense Studies

Form/Duration

Lactobacillus LGG® + Bifidobacterium BB-12®

Study Details and Results

Randomized, double-blind, placebo-controlled trial 12 weeks | 198 human subjects ↓ Respiratory discomfort duration & severity ↑ Health-related quality of life (HRQL)

Reference

DOI: 10.1017/S0007114512004138

Lactobacillus LGG® + Bifidobacterium BB-12®

In vivo studies ↑ Gut microflora balance ↑ Beneficial bacteria growth ↑ Microbiome health

DOI: 10.1080/23311932.2018.1452839

Lactobacillus LGG®

Randomized, double-blind, placebo-controlled trial 3 months | 281 children ↑ Respiratory health ↓ Respiratory instances lasting more than three days ↓ Days with respiratory discomfort

DOI: 10.1016/j.clnu.2009.09.008

Bifidobacterium BB-12®

Randomized, double-blind, placebo-controlled trial 6 weeks | 211 human subjects ↑ IgG ↑IgA levels ↑ Total antibody concentration

DOI: 10.1017/S000711451100420X

EpiCor®

Randomized, double-blind, placebo-controlled trial 12 weeks | 96 human subjects ↑ Nasal & airflow comfort ↓ Nasal discharge ↓ Nasal concerns severity & duration

DOI: 10.1007/s12325-009-0057-y

Zinc

Investigative study 14 days 54 human subjects ↑ Natural Killer cell functionality ↓ Circulating innate lymphoid cell counts & frequencies

DOI: 10.1186/s12967-025-06259-y

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